Companies by HQ LocationTech Companies and Startups Headquartered in Cambridge

Sora Fuel makes jet fuel from just air, water, and renewable energy. Sora Fuel combine carbon capture and utilization into a single process, dramatically reducing the amount of energy required to produce SAF, enabling a truly affordable, carbon-negative dr

Liquid AI is a developer of AI applications that help improve human experience. It focuses on researching and developing tools that use artificial intelligence to improve creative workflows and help clients manage their workflow efficiently.

Pascal is an early stage Boston-based clean technology company, commercializing solid refrigerant heat pumps and air conditioners. The HVAC sector currently accounts for 30% of total global energy usage while also directly emitting 1.5 GTon CO2 eq. of gree

Sesame Sustainability is a SAAS company that offers industrial decarbonization platform for modeling, optimization, and analysis.

Synthpop is a company that develops AI-driven solutions to streamline healthcare workflows and improve patient care. The company's platform leverages advanced technologies to automate data entry, insurance verification, and other administrative tasks, free

VULCAN ELEMENTS is changing the way to electrify aerospace, defense, and auto with decarbonization.

MacroCycle is developing a technology to curb the usage of fossil fuel derived plastic through a circular, sustainable and zero-carbon plastic upcycling process. The company's proprietary process based on the synthesis of cyclic macromolecules enables us t

Pi Health is a provider of platforms to assist oncology-related clinical trials with identifying sites and helping sponsors manage sites

Developer of the world's first cloud-native operating system, DBOS, and the DBOS Cloud transactional serverless computing platform. A simpler, more secure way to build fault-tolerant cloud applications. Based on 3 years of joint MIT-Stanford research, led

Symbionics is a brain-computer interface company that focuses on the development of interface devices to integrate humans and machines.

Koya AI helps data aggregators such as marketplaces and procurement platforms to manage catalog data seamlessly. Instead of spending days manually chasing down, standardizing, and enriching product data, marketplaces can rely on Koya’s data-as-a-service of

NeuroBionics is pioneering the future of precision bioelectronic medicine by inventing the next generation of implanted devices that will seamlessly interface with the human body.

We develop scalable quantum computers to tackle the world’s hardest computational challenges. Join us: https://jobs.polymer.co/atlantic-quantum.

With Stack AI, any organization can build and deploy custom AI Assistants in minutes. Our no-code interface allows teams to leverage AI for searching through knowledge bases, automating workflows, and building chatbots. Hundreds of companies use Stack AI

Founded by Flagship Pioneering, Empress re-imagines the process of small molecule drug discovery. Our bioplatform harnesses the power of evolution, human molecular and genetic data, and artificial intelligence to focus on endogenous sources of inherently d

Orbital Therapeutics aims to enhance global health by unleashing the full potential of RNA-based medicines to treat human disease in ways that were not previously possible.

Diagonal Therapeutics is a biotechnology startup that is pioneering a novel technique to finding and producing agonist antibodies. Diagonal Therapeutics platform combines novel computational and experimental methodologies to solve the traditional obstacles

Cartwheel offers mental health support to students in order to help schools regain balance in the midst of the student mental health crisis. It works hand in hand to empower school staff, reduce family stress, and improve all students' mental health outcom

Montai is harnessing nature's power through digital technology to treat and prevent chronic disease, hence improving health outcomes for as many people as possible. To address this crucial global concern, the business is pioneering cutting-edge technology

Foundation Alloy leverage advanced materials technology to design novel alloys optimized for additive manufacturing.

ProFound Therapeutics is creating profound impacts on the understanding of biology and disease and the ability to create therapeutics.

Istari makes digital engineering ecosystems a reality where all technologies are created digitally, free from real-world costs, schedules, and environmental impacts.

DEM Bio is pioneering the next generation of immunotherapeutics that unleash macrophages and immune phagocytes to eliminate tumors by targeting ‘Don’t eat me’ (DEM) and ‘Eat me’ (EM) signals on cancer cells and macrophages. Founded by Longwood Fund and is

Via Scientific to help scientists and bioinformaticians generate novel science that improves the world. It was founded in 2022.

Wild Microbes is a next-generation microbial platform that makes everything from plastics to proteins. They develop new microbial strains, making scaling sustainable products faster and cheaper than ever.

Pramana, Inc is a new health technology company from nference that enables digital transformation for next-generation pathology at medical centers and pathology labs. Pramana offers a first-in-class Digital Pathology as a Service (DPaaS) solution by provid

Suno is a music start-up that enables anyone to make the songs they want. The company aims to help people rediscover the joy of play and exploration.

Mantel is developing the first molten-salt based carbon capture technology. Our molten borates are designed to operate at the high temperatures found inside boilers, kilns, and furnaces – enabling highly efficient carbon capture that has not been possible

Sleepagotchi rewards users with a digital collectible for sticking to a consistent sleep schedule that they set for themselves in order to promote healthy sleeping habits.

FORAY bioscience is a biotechnology company that uses biomanufacturing techniques to produce wood products.

Digital twins are revolutionizing industries from aerospace to agriculture. Istari makes them simple and more secure, unlocking models and simulations for better products - better everything. A faster, cheaper, greener digital future awaits. With Istari,

NuMind is a manufacturing company currently based in Cambridge, Massachusetts, United States. It has been founded in 2022 by Etienne Bernard and Samuel Bernard.

Entro is a revolutionary cyber security platform that provides protection for secrets and programmatic access to cloud services and data. They assist in accelerating business growth and success by building a safe cloud environment.

Wecover Platforms creates AI-powered PaaS for Property and Casualty Insurance Industry

Omnipulse Biosciences offers single injection quantities suitable for clinical trials and commercial distribution to low-income countries

Datalign Advisory is a financial advisory firm that connects clients with a network of financial advisers.

StataDX is building the world's first point-of-care diagnostics platform for Neurology.

Tailbox is an MIT-backed startup bringing locations to life through generative AI powered stories. Our location-based social platform for explorers focuses on uncovering hidden gems and unique narratives in every city through immersive storytelling and per

Nvelop Therapeutics is a biotechnology company that provides gene editing technology services for unmet major disease needs.

Fizz is building a debit card that helps college students in the U.S. started building out their credit without having to learn lessons about overzealous credit use the hard way.

Kano Therapeutics enables safe, effective, and flexible correction of gene-length stretches of DNA through a new class of biomaterials.

Beta Finance is a permissionless money market protocol for lending, borrowing, and short-selling crypto assets. It aims to offset crypto volatility and bring market stability. Its one-click solution enables traders without technical know-how to manage and

Thousands of collectors use evaluate.market to analyze NFTs. We are a remote, venture-backed company that is changing how people buy, sell, and analyze digital collectibles. Connect with us on Twitter and join our Discord to learn more.

Dianthus is the world’s only AI-first E-commerce company – built from the ground up to help small to medium E-commerce brands.

SanaHeal provider of a bioadhesive tape designed to bind to tissues or organs

K36 Therapeutics mission to translate epigenetic modulation of oncogenic pathways into first-in-class small molecule therapies.

Yard Stick measures soil carbon. Scientists and farmers alike know that climate-friendly agricultural practices have the potential to remove atmospheric CO2 at gigaton/year scale. When these practices are adopted, more carbon is stored in soils, improving

Apollon offers more simple diagnostic techniques. It can detect inflammatory substances in a single blood sample and measure blood sugar without collecting blood. All of this is possible because light can unlock the signal of chemical bonds in molecules wi

Centessa Pharmaceuticals is a next-generation biopharmaceutical company that aims to reshape the traditional drug development process. The company applies an asset-centric R&D model at scale to advance a portfolio of highly validated programs led by indust

Flare Therapeutics is a biotechnology company opening up a new therapeutic space with a novel approach to decipher the biology of transcription factors to develop small molecule medicines. Based on insights from the seminal work of its scientific founders,

Tutor Intelligence is on a mission to bring robots to places they've never been before. We have made it cheap and easy for businesses of all sizes to hire robots as drop-in solutions for picking, placing, pal/depal, material handling, sorting, kitting, ins

Robigo is a biopesticide engineering the plant microbiome to reduce disease in crops.

Atavistik Bio is a pre-clinical biotechnology company pioneering the identification of metabolite-protein interactions that have the potential to lead to the discovery and development of first-in-class drug candidates powered by distinct allosteric control

Themis AI, a spinoff from CSAIL MIT, was founded by MIT alumni and professors to empower the world to create, advance, and deploy trustworthy AI. Themis' technology enables trustworthy AI in high risk scenarios, rare events and anywhere imbalances and bias

Gesund.ai orchestrates the AI as-a-Medical Device lifecycle, providing privacy-centered access to diverse yet standardized medical data sources, and a unique analytical toolbox that fosters clinical validation, regulatory clearance and effective marketing.

Crossbow Therapeutics is a seed-stage, stealth-mode oncology startup company. The company develops antibody engineering for intracellular cancer targets.

Stack is a B2B SaaS computer vision information system company that aims to rethink the way warehouses are managed across the United States.

Metaphore Biotechnologies use biomimicry and machine learning to unveil the revolutionary medicinal potential of functional molecular mimics. The MIMiCTM platform, developed by the business, is a computationally driven bio platform for developing novel the

Convergent Therapeutics is a clinical-stage biotechnology company exploring the full potential of dual-targeted combination strategies to treat cancer. Convergent has developed a therapeutic platform that is capable of targeting validated and novel cancer

Matchpoint is a biotechnology company harnessing the power of covalency to discover precision covalent medicines to transform the treatment of immune diseases and other serious illnesses. The company's proprietary Advanced Covalent Exploration (ACE) platfo

ElevateBio is an operator of a portfolio of cell and gene therapy companies intended to develop, manufacture, and commercialize life-transforming medicines. The company creates a portfolio through partnerships with the world's innovative scientists and inv

Fourth Power is an energy storage startup that uses thermal batteries. Through utility-scale thermal storage, the technique transforms renewable energy into an on-demand energy source.

Anumana is an AI-driven company that develops ECG algorithms enabling early disease diagnosis and intervention.

hC Bioscience is an innovator and pioneer of protein editing using context agnostic engineered tRNA. Their First in Class approach for protein editing advances beyond genome editing to direct modification of the proteome.

Abata Therapeutics, a company focused on translating the biology of regulatory T cells (Tregs) into transformational medicines for patients living with progressive multiple sclerosis (MS) and other severe autoimmune and inflammatory diseases.

Ketryx is an information technology company that features software development tools built for developers, by developers.

Garuda Therapeutics is developing off-the-shelf hematopoietic stem cell (HSC) therapies to treat a broad range of severe and life-threatening diseases.

FYTO is a technology company that develops systems that grow high quality crops using much less resources.

Osmoses engages in decarbonizing gas separations to eliminate one gigaton of carbon emissions per year.

Skylark Bio is a biotechnology company that develops gene therapies to treat hearing losses. The company was founded in 2021 and is based in Cambridge, Massachusetts, United States.

Photys Therapeutics’ proprietary bifunctional small molecules platform unlocks fine-tuned control of protein post-translational modifications, going beyond degradation to restore protein function, repair signaling, and amplify endogenous disease-fighting m

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Heyday Health offers primary care for adults providing in-home and video visits, clinical team, and continuous accessibility.

Prologue Medicines creates transformative medicines by systematically discovering and evaluating viral proteins and their unique features.

Axoft’s bioinspired, scalable implant promotes long-term communication with the nervous system - transforming clinical outcomes, individual health, and the human experience.

OpenEvidence Information overload is a common problem in many high-value domains. It's a huge challenge in medicine. With such a rate of change, it is practically impossible for the world's physicians, medical scientists, and healthcare professionals to k

ReNAgade Therapeutics focuses on the boundless potential of RNA therapeutics to treat disease. RNA delivery systems with a comprehensive RNA platform that allows for an all-RNA system for coding, editing, and gene insertion to produce new medications.

SalioGen Therapeutics advances in curative genetic therapies using its Exact DNA Integration Technology (EDIT) platform, a mammal-derived genome engineering technology. It is focused on providing durable, safe, and affordable non-viral gene therapies to mo

Walden Biosciences is a biotechnology company focused on transforming the treatment of kidney disease. Founded by world-renowned experts in renal disease, Walden is applying its unique, systems-based approach to address the intersection between the patholo

Kiwi biosciences is a biotech company that develops enzymes to make food for patients who suffer from Irritable Bowel Syndrome (IBS). The company was founded in 2020 and is based in Somerville, Massachusetts, United States.

Tagomics transform disease diagnosis through comprehensive multitopic profiling.

NextPoint Therapeutics develops medications to expand the benefit of immunotherapies to cancer patients. The company offers immunotherapies for a validated checkpoint axis that is independent of PD-1/L1 and modulates both adaptive and innate immune systems

Parallel Bio created a human 'immune system in a dish' to discover drugs and immunotherapies more likely to work in patients.

Bicara Therapeutics, a wholly-owned subsidiary of Biocon based in Boston, U.S., is developing a pipeline of bifunctional antibodies that exploit the recent advances in immuno-oncology. Bicara enables access to the thriving innovation ecosystem in the U.S.

Woho enables a new way to build, assembling a team, network, and system to construct from low to high-rise structures with unprecedented quality, precision, and efficiency. The company was founded in 2020 and based in Cambridge, Massachusetts.

Clasp Therapeutics offers to reach of immuno-oncology with novel precision medicines that enable the immune system to identify and specifically destroy hard-to-treat tumors bearing common driver mutations, regardless of tumor type.

Vigil Neuroscience is the world’s first microglia-focused therapeutics company. Our purpose is clear: to treat rare and common neurodegenerative diseases by restoring the vigilance of the microglia, the sentinel cells of the brain’s immune system. We are u

IoT-enabled analytics platform providing data-driven optimization of industrial liquid systems for manufacturing

Faze Medicines is a biotechnology company harnessing the groundbreaking new science of biomolecular condensates to create medical breakthroughs.

Carbon Counts is creating a unique mobile game that will engage people to individually and collectively impact climate change

Verve's mission is to improve the limits of worker safety and well-being by pioneering the integration of robotics into functional apparel. They commercialize a lightweight, one-size fits most wearable that powers and protects workers all day long, so they

Silvertree is on a mission to empower the world’s aging population. We are developing next-gen wearable technology that provides the right form of safety and connection for active older adults. Aging is a personal experience, yet aging with dignity and ind

TalkTo Inc. develops mobile applications. The Company offers an application that enables users to text directly to stores, restaurants, hotels, and other types of businesses. TalkTo serves the consumer discretionary sector.

Nabla is an autoreverse platform that enables the rapid discovery of previously unattainable protein variants with supernatural qualities. Nabla Bio makes new medicines and improve nutrition by engineering novel proteins.

Hosta Labs automates the analysis of images and videos of interior structures for property insurance carriers to provide a full in-depth view of accurate replacement values and risks in the underwriting process and on raw material quantities and mitigation

Akooda helps employees to navigate the digital, hybrid, and remote work world using AI and data science.

SiTration improves ultra-durable filtration membranes intended for efficient separations in the harshest environments.Brendan Smith established the company in Cambridge, Massachusetts in 2020.

AavantiBio is a biopharmaceutical company that provides gene transfer and gene editing therapies to treat genetic diseases.

Seismic Therapeutic is a biotechnology company integrating machine learning across the entire biologics discovery process to accelerate immunology drug development. Using our IMPACT™ platform, we are addressing the central challenges of biologics discovery

As schools and businesses return to work, they will be met with a number of new challenges: keeping students and employees safe, tracking outbreaks, and communicating to the public that they are taking responsible precautions. CoVerified provides a profe